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Active epithelial Hippo signaling in idiopathic pulmonary fibrosis

Hippo/YAP signaling plays pleiotropic roles in the regulation of cell proliferation and differentiation during organogenesis and tissue repair. Herein we demonstrate increased YAP activity in respiratory epithelial cells in lungs of patients with idiopathic pulmonary fibrosis (IPF), a common, lethal...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Gokey, Jason J., Sridharan, Anusha, Xu, Yan, Green, Jenna, Carraro, Gianni, Stripp, Barry R., Perl, Anne-Karina T., Whitsett, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926907/
https://ncbi.nlm.nih.gov/pubmed/29563341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98738
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