Active epithelial Hippo signaling in idiopathic pulmonary fibrosis

Hippo/YAP signaling plays pleiotropic roles in the regulation of cell proliferation and differentiation during organogenesis and tissue repair. Herein we demonstrate increased YAP activity in respiratory epithelial cells in lungs of patients with idiopathic pulmonary fibrosis (IPF), a common, lethal...

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Publicat a:JCI Insight
Autors principals: Gokey, Jason J., Sridharan, Anusha, Xu, Yan, Green, Jenna, Carraro, Gianni, Stripp, Barry R., Perl, Anne-Karina T., Whitsett, Jeffrey A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926907/
https://ncbi.nlm.nih.gov/pubmed/29563341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98738
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