Nanoparticles Based on Poly (β-Amino Ester) and HPV16-Targeting CRISPR/shRNA as Potential Drugs for HPV16-Related Cervical Malignancy

Persistent high-risk HPV infection is the main cause of cervical cancer. The HPV oncogene E7 plays an important role in HPV carcinogenesis. Currently, HPV vaccines do not offer an effective treatment for women who already present with cervical disease, and recommended periodical cervical screenings...

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Bibliographic Details
Published in:Mol Ther
Main Authors: Zhu, Da, Shen, Hui, Tan, Songwei, Hu, Zheng, Wang, Liming, Yu, Lan, Tian, Xun, Ding, Wencheng, Ren, Ci, Gao, Chun, Cheng, Jing, Deng, Ming, Liu, Rong, Hu, Junbo, Xi, Ling, Wu, Peng, Zhang, Zhiping, Ma, Ding, Wang, Hui
Format: Artigo
Language:Inglês
Published: American Society of Gene & Cell Therapy 2018
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171328/
https://ncbi.nlm.nih.gov/pubmed/30241742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.07.019
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