Nanoparticles Based on Poly (β-Amino Ester) and HPV16-Targeting CRISPR/shRNA as Potential Drugs for HPV16-Related Cervical Malignancy

Persistent high-risk HPV infection is the main cause of cervical cancer. The HPV oncogene E7 plays an important role in HPV carcinogenesis. Currently, HPV vaccines do not offer an effective treatment for women who already present with cervical disease, and recommended periodical cervical screenings...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Zhu, Da, Shen, Hui, Tan, Songwei, Hu, Zheng, Wang, Liming, Yu, Lan, Tian, Xun, Ding, Wencheng, Ren, Ci, Gao, Chun, Cheng, Jing, Deng, Ming, Liu, Rong, Hu, Junbo, Xi, Ling, Wu, Peng, Zhang, Zhiping, Ma, Ding, Wang, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171328/
https://ncbi.nlm.nih.gov/pubmed/30241742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.07.019
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