Formation and phenotypic characterization of CD49a, CD49b and CD103 expressing CD8 T cell populations in human metastatic melanoma

Integrins α1β1 (CD49a), α2β1 (CD49b) and αEβ7 (CD103) mediate retention of lymphocytes in peripheral tissues, and their expression is upregulated on tumor infiltrating lymphocytes (TIL) compared to circulating lymphocytes. Little is known about what induces expression of these retention integrins (R...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Melssen, Marit M., Olson, Walter, Wages, Nolan A., Capaldo, Brian J., Mauldin, Ileana S., Mahmutovic, Adela, Hutchison, Ciara, Melief, Cornelis J.M., Bullock, Timothy N., Engelhard, Victor H., Slingluff, Craig L.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2018
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169593/
https://ncbi.nlm.nih.gov/pubmed/30288359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1490855
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