Formation and phenotypic characterization of CD49a, CD49b and CD103 expressing CD8 T cell populations in human metastatic melanoma

Integrins α1β1 (CD49a), α2β1 (CD49b) and αEβ7 (CD103) mediate retention of lymphocytes in peripheral tissues, and their expression is upregulated on tumor infiltrating lymphocytes (TIL) compared to circulating lymphocytes. Little is known about what induces expression of these retention integrins (R...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Melssen, Marit M., Olson, Walter, Wages, Nolan A., Capaldo, Brian J., Mauldin, Ileana S., Mahmutovic, Adela, Hutchison, Ciara, Melief, Cornelis J.M., Bullock, Timothy N., Engelhard, Victor H., Slingluff, Craig L.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169593/
https://ncbi.nlm.nih.gov/pubmed/30288359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1490855
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