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Heterogeneity in tertiary lymphoid structure B-cells correlates with patient survival in metastatic melanoma

BACKGROUND: Tertiary lymphoid structures (TLSs) are immune aggregates in peripheral tissues that may support adaptive immune responses. Their presence has been associated with clinical response to checkpoint blockade therapy (CBT), but it is unknown whether TLS have prognostic significance independe...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Lynch, Kevin T, Young, Samuel J, Meneveau, Max O, Wages, Nolan A, Engelhard, Victor H, Slingluff Jr, Craig L, Mauldin, Ileana S
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190052/
https://ncbi.nlm.nih.gov/pubmed/34103353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-002273
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