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Heterogeneity in tertiary lymphoid structure B-cells correlates with patient survival in metastatic melanoma

BACKGROUND: Tertiary lymphoid structures (TLSs) are immune aggregates in peripheral tissues that may support adaptive immune responses. Their presence has been associated with clinical response to checkpoint blockade therapy (CBT), but it is unknown whether TLS have prognostic significance independe...

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Detalles Bibliográficos
Publicado en:J Immunother Cancer
Autores principales: Lynch, Kevin T, Young, Samuel J, Meneveau, Max O, Wages, Nolan A, Engelhard, Victor H, Slingluff Jr, Craig L, Mauldin, Ileana S
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Publishing Group 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190052/
https://ncbi.nlm.nih.gov/pubmed/34103353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-002273
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