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Heterogeneity in tertiary lymphoid structure B-cells correlates with patient survival in metastatic melanoma

BACKGROUND: Tertiary lymphoid structures (TLSs) are immune aggregates in peripheral tissues that may support adaptive immune responses. Their presence has been associated with clinical response to checkpoint blockade therapy (CBT), but it is unknown whether TLS have prognostic significance independe...

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Bibliografski detalji
Izdano u:J Immunother Cancer
Glavni autori: Lynch, Kevin T, Young, Samuel J, Meneveau, Max O, Wages, Nolan A, Engelhard, Victor H, Slingluff Jr, Craig L, Mauldin, Ileana S
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190052/
https://ncbi.nlm.nih.gov/pubmed/34103353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-002273
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