Formation and phenotypic characterization of CD49a, CD49b and CD103 expressing CD8 T cell populations in human metastatic melanoma

Integrins α1β1 (CD49a), α2β1 (CD49b) and αEβ7 (CD103) mediate retention of lymphocytes in peripheral tissues, and their expression is upregulated on tumor infiltrating lymphocytes (TIL) compared to circulating lymphocytes. Little is known about what induces expression of these retention integrins (R...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Melssen, Marit M., Olson, Walter, Wages, Nolan A., Capaldo, Brian J., Mauldin, Ileana S., Mahmutovic, Adela, Hutchison, Ciara, Melief, Cornelis J.M., Bullock, Timothy N., Engelhard, Victor H., Slingluff, Craig L.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169593/
https://ncbi.nlm.nih.gov/pubmed/30288359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1490855
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