TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiotherapy

Cancer-induced myeloid-derived suppressor cells (MDSC) play an important role in tumor immune evasion. MDSC programming or polarization has been proposed as a strategy for leveraging the developmental plasticity of myeloid cells to reverse MDSC immune suppressive functions, or cause them to acquire...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Jayaraman, Padmini, Parikh, Falguni, Newton, Jared M., Hanoteau, Aurelie, Rivas, Charlotte, Krupar, Rosemarie, Rajapakshe, Kimal, Pathak, Ravi, Kanthaswamy, Kavin, MacLaren, Cassie, Huang, Shixia, Coarfa, Cristian, Spanos, Chad, Edwards, Dean P., Parihar, Robin, Sikora, Andrew G.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2018
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169570/
https://ncbi.nlm.nih.gov/pubmed/30288358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1490853
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