Tumor-expressed iNOS controls induction of functional myeloid derived suppressor cells (MDSC) through modulation of VEGF release()

Inducible nitric oxide synthase (iNOS) is a hallmark of chronic inflammation which is also overexpressed in melanoma and other cancers. While iNOS is a known effector of myeloid-derived suppressor cell (MDSC)-mediated immunosuppression, its pivotal position at the interface of inflammation and cance...

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Detalhes bibliográficos
Main Authors: Jayaraman, Padmini, Parikh, Falguni, Lopez-Rivera, Esther, Hailemichael, Yared, Clark, Amelia, Ma, Ge, Cannan, David, Ramacher, Marcel, Kato, Masashi, Overwijk, Willem W., Chen, Shu-Hsia, Umansky, Viktor Y., Sikora, Andrew G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358566/
https://ncbi.nlm.nih.gov/pubmed/22529296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103553
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