Tumor-expressed iNOS controls induction of functional myeloid derived suppressor cells (MDSC) through modulation of VEGF release()

Inducible nitric oxide synthase (iNOS) is a hallmark of chronic inflammation which is also overexpressed in melanoma and other cancers. While iNOS is a known effector of myeloid-derived suppressor cell (MDSC)-mediated immunosuppression, its pivotal position at the interface of inflammation and cance...

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Bibliographic Details
Main Authors:	Jayaraman, Padmini, Parikh, Falguni, Lopez-Rivera, Esther, Hailemichael, Yared, Clark, Amelia, Ma, Ge, Cannan, David, Ramacher, Marcel, Kato, Masashi, Overwijk, Willem W., Chen, Shu-Hsia, Umansky, Viktor Y., Sikora, Andrew G.
Format:	Artigo
Language:	Inglês
Published:	2012
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3358566/ https://ncbi.nlm.nih.gov/pubmed/22529296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103553
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Tumor-expressed iNOS controls induction of functional myeloid derived suppressor cells (MDSC) through modulation of VEGF release()

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