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Mechanisms of skeletal muscle wasting in a mouse model for myotonic dystrophy type 1

Myotonic dystrophy type 1 (DM1) is a multi-systemic disease resulting in severe muscle weakening and wasting. DM1 is caused by expansion of CTG repeats in the 3′ untranslated region of the dystrophia myotonica protein kinase (DMPK) gene. We have developed an inducible, skeletal muscle-specific mouse...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Morriss, Ginny R, Rajapakshe, Kimal, Huang, Shixia, Coarfa, Cristian, Cooper, Thomas A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077786/
https://ncbi.nlm.nih.gov/pubmed/29771332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy192
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