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Computer Folding of RNA Tetraloops: Identification of Key Force Field Deficiencies

The computer aided folding of biomolecules, particularly RNAs, is one of the most difficult challenges in computational structural biology. RNA tetraloops are fundamental RNA motifs playing key roles in RNA folding and RNA-RNA and RNA-protein interactions. Although state-of-the-art Molecular Dynamic...

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Bibliografski detalji
Izdano u:J Chem Theory Comput
Glavni autori: Kührová, Petra, Best, Robert B., Bottaro, Sandro, Bussi, Giovanni, Šponer, Jiří, Otyepka, Michal, Banáš, Pavel
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169534/
https://ncbi.nlm.nih.gov/pubmed/27438572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.6b00300
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