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Stevioside Prevents Wear Particle-Induced Osteolysis by Inhibiting Osteoclastogenesis and Inflammatory Response via the Suppression of TAK1 Activation

Aseptic loosening and periprosthetic osteolysis are the leading causes of total joint arthroplasty failure, which occurs as a result of chronic inflammatory response and enhanced osteoclast activity. Here we showed that stevioside, a natural compound isolated from Stevia rebaudiana, exhibited preven...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Front Pharmacol
Κύριοι συγγραφείς: Meng, Jiahong, Zhou, Chenhe, Hu, Bin, Luo, Mengmeng, Yang, Yute, Wang, Yangxin, Wang, Wei, Jiang, Guangyao, Hong, Jianqiao, Li, Sihao, Wu, Haobo, Yan, Shigui, Yan, Weiqi
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Frontiers Media S.A. 2018
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169369/
https://ncbi.nlm.nih.gov/pubmed/30319406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01053
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