Immunotolerant p50/NFκB Signaling and Attenuated Hepatic IFNβ Expression Increases Neonatal Sensitivity to Endotoxemia

Sepsis is a major cause of neonatal morbidity and mortality. The current paradigm suggests that neonatal susceptibility to infection is explained by an innate immune response that is functionally immature. Recent studies in adults have questioned a therapeutic role for IFNβ in sepsis; however, the r...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: McKenna, Sarah, Burey, Taylor, Sandoval, Jeryl, Nguyen, Leanna, Castro, Odalis, Gudipati, Suma, Gonzalez, Jazmin, El Kasmi, Karim C., Wright, Clyde J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168645/
https://ncbi.nlm.nih.gov/pubmed/30319651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02210
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados