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Inhibiting IκBβ–NFκB signaling attenuates the expression of select pro-inflammatory genes
Multiple mediators of septic shock are regulated by the transcription factor nuclear factor κB (NFκB). However, complete NFκB inhibition can exacerbate disease, necessitating evaluation of targeted strategies to attenuate the pro-inflammatory response. Here, we demonstrate that in murine macrophages...
Guardat en:
| Publicat a: | J Cell Sci |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Company of Biologists
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457027/ https://ncbi.nlm.nih.gov/pubmed/25908863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.168351 |
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