Neuropsychiatric Systemic Lupus Erythematosus Is Dependent on Sphingosine-1-Phosphate Signaling

About 40% of patients with systemic lupus erythematosus experience diffuse neuropsychiatric manifestations, including impaired cognition and depression. Although the pathogenesis of diffuse neuropsychiatric SLE (NPSLE) is not fully understood, loss of brain barrier integrity, autoreactive antibodies...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Mike, Elise V., Makinde, Hadijat M., Der, Evan, Stock, Ariel, Gulinello, Maria, Gadhvi, Gaurav T., Winter, Deborah R., Cuda, Carla M., Putterman, Chaim
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168636/
https://ncbi.nlm.nih.gov/pubmed/30319641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02189
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