Lipocalin 2 is a Pathogenic Determinant and Biomarker of Neuropsychiatric Lupus

Neuropsychiatric manifestations in lupus (NPSLE) affect ~20-40% of patients. In the central nervous system, lipocalin-2 (LCN2) can promote injury through mechanisms directly linked to NPSLE, including brain barrier disruption, neurotoxicity, and glial activation. Since LCN2 is elevated in lupus and...

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Detalhes bibliográficos
Publicado no:J Autoimmun
Main Authors: Mike, Elise V., Makinde, Hadijat M., Gulinello, Maria, Vanarsa, Kamala, Herlitz, Leal, Gadhvi, Gaurav, Winter, Deborah R., Mohan, Chandra, Hanly, John G., Mok, CC, Cuda, Carla M., Putterman, Chaim
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310639/
https://ncbi.nlm.nih.gov/pubmed/30174216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2018.08.005
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