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Chemogenetic generation of hydrogen peroxide in the heart induces severe cardiac dysfunction

Oxidative stress plays an important role in the pathogenesis of many disease states. In the heart, reactive oxygen species are linked with cardiac ischemia/reperfusion injury, hypertrophy, and heart failure. While this correlation between ROS and cardiac pathology has been observed in multiple model...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Steinhorn, Benjamin, Sorrentino, Andrea, Badole, Sachin, Bogdanova, Yulia, Belousov, Vsevolod, Michel, Thomas
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168530/
https://ncbi.nlm.nih.gov/pubmed/30279532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06533-2
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