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Chemogenetic generation of hydrogen peroxide in the heart induces severe cardiac dysfunction

Oxidative stress plays an important role in the pathogenesis of many disease states. In the heart, reactive oxygen species are linked with cardiac ischemia/reperfusion injury, hypertrophy, and heart failure. While this correlation between ROS and cardiac pathology has been observed in multiple model...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Steinhorn, Benjamin, Sorrentino, Andrea, Badole, Sachin, Bogdanova, Yulia, Belousov, Vsevolod, Michel, Thomas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168530/
https://ncbi.nlm.nih.gov/pubmed/30279532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06533-2
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