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Chemogenetic generation of hydrogen peroxide in the heart induces severe cardiac dysfunction

Oxidative stress plays an important role in the pathogenesis of many disease states. In the heart, reactive oxygen species are linked with cardiac ischemia/reperfusion injury, hypertrophy, and heart failure. While this correlation between ROS and cardiac pathology has been observed in multiple model...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Steinhorn, Benjamin, Sorrentino, Andrea, Badole, Sachin, Bogdanova, Yulia, Belousov, Vsevolod, Michel, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168530/
https://ncbi.nlm.nih.gov/pubmed/30279532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06533-2
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