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Chemogenetic generation of hydrogen peroxide in the heart induces severe cardiac dysfunction

Oxidative stress plays an important role in the pathogenesis of many disease states. In the heart, reactive oxygen species are linked with cardiac ischemia/reperfusion injury, hypertrophy, and heart failure. While this correlation between ROS and cardiac pathology has been observed in multiple model...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Steinhorn, Benjamin, Sorrentino, Andrea, Badole, Sachin, Bogdanova, Yulia, Belousov, Vsevolod, Michel, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168530/
https://ncbi.nlm.nih.gov/pubmed/30279532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06533-2
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