Načítá se...
GSK3-β promotes calpain-1–mediated desmin filament depolymerization and myofibril loss in atrophy
Myofibril breakdown is a fundamental cause of muscle wasting and inevitable sequel of aging and disease. We demonstrated that myofibril loss requires depolymerization of the desmin cytoskeleton, which is activated by phosphorylation. Here, we developed a mass spectrometry–based kinase-trap assay and...
Uloženo v:
| Vydáno v: | J Cell Biol |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Rockefeller University Press
2018
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6168250/ https://ncbi.nlm.nih.gov/pubmed/30061109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201802018 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|