Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma

The intrinsic drivers of migration in glioblastoma (GBM) are poorly understood. To better capture the native molecular imprint of GBM and its developmental context, here we isolate human stem cell populations from GBM (GSC) and germinal matrix tissues and map their chromatin accessibility via ATAC-s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Tome-Garcia, Jessica, Erfani, Parsa, Nudelman, German, Tsankov, Alexander M., Katsyv, Igor, Tejero, Rut, Bin Zhang, Walsh, Martin, Friedel, Roland H., Zaslavsky, Elena, Tsankova, Nadejda M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167382/
https://ncbi.nlm.nih.gov/pubmed/30275445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06258-2
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