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Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma

The intrinsic drivers of migration in glioblastoma (GBM) are poorly understood. To better capture the native molecular imprint of GBM and its developmental context, here we isolate human stem cell populations from GBM (GSC) and germinal matrix tissues and map their chromatin accessibility via ATAC-s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Tome-Garcia, Jessica, Erfani, Parsa, Nudelman, German, Tsankov, Alexander M., Katsyv, Igor, Tejero, Rut, Bin Zhang, Walsh, Martin, Friedel, Roland H., Zaslavsky, Elena, Tsankova, Nadejda M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167382/
https://ncbi.nlm.nih.gov/pubmed/30275445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06258-2
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