Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma

The intrinsic drivers of migration in glioblastoma (GBM) are poorly understood. To better capture the native molecular imprint of GBM and its developmental context, here we isolate human stem cell populations from GBM (GSC) and germinal matrix tissues and map their chromatin accessibility via ATAC-s...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Tome-Garcia, Jessica, Erfani, Parsa, Nudelman, German, Tsankov, Alexander M., Katsyv, Igor, Tejero, Rut, Bin Zhang, Walsh, Martin, Friedel, Roland H., Zaslavsky, Elena, Tsankova, Nadejda M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167382/
https://ncbi.nlm.nih.gov/pubmed/30275445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06258-2
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