Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes seen in neonatal necrotizing enterocolitis

Necrotizing enterocolitis (NEC) remains the leading cause of gastrointestinal morbidity and mortality in premature infants. Human and animal studies suggest a role for Paneth cells in NEC pathogenesis. Paneth cells play critical roles in host-microbial interactions and epithelial homeostasis. The ra...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Lueschow, Shiloh R., Stumphy, Jessica, Gong, Huiyu, Kern, Stacy L., Elgin, Timothy G., Underwood, Mark A., Kalanetra, Karen M., Mills, David A., Wong, Melissa H., Meyerholz, David K., Good, Misty, McElroy, Steven J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166990/
https://ncbi.nlm.nih.gov/pubmed/30273395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204967
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