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Paneth Cells and Necrotizing Enterocolitis: A novel hypothesis for disease pathogenesis
Current models of necrotizing enterocolitis (NEC) propose intraluminal microbes destroy intestinal mucosa and activate an inflammatory cascade that ends in necrosis. We suggest an alternate hypothesis wherein NEC is caused by injury to Paneth cells (PCs) in the intestinal crypts. PCs are specialized...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3609425/ https://ncbi.nlm.nih.gov/pubmed/23006982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000342340 |
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