Paneth cell ablation in the presence of Klebsiella pneumoniae induces necrotizing enterocolitis (NEC)-like injury in the small intestine of immature mice

Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in premature infants. During NEC pathogenesis, bacteria are able to penetrate innate immune defenses and invade the intestinal epithelial layer, causing subsequent inflammation and tissue necrosis. Normally, Paneth cells a...

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Main Authors: Zhang, Chunxian, Sherman, Michael P., Prince, Lawrence S., Bader, David, Weitkamp, Jörn-Hendrik, Slaughter, James C., McElroy, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists Limited 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380715/
https://ncbi.nlm.nih.gov/pubmed/22328592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.009001
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