Paneth cell ablation in the presence of Klebsiella pneumoniae induces necrotizing enterocolitis (NEC)-like injury in the small intestine of immature mice

Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in premature infants. During NEC pathogenesis, bacteria are able to penetrate innate immune defenses and invade the intestinal epithelial layer, causing subsequent inflammation and tissue necrosis. Normally, Paneth cells a...

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Bibliografiske detaljer
Main Authors: Zhang, Chunxian, Sherman, Michael P., Prince, Lawrence S., Bader, David, Weitkamp, Jörn-Hendrik, Slaughter, James C., McElroy, Steven J.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Limited 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380715/
https://ncbi.nlm.nih.gov/pubmed/22328592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.009001
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