Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes seen in neonatal necrotizing enterocolitis

Necrotizing enterocolitis (NEC) remains the leading cause of gastrointestinal morbidity and mortality in premature infants. Human and animal studies suggest a role for Paneth cells in NEC pathogenesis. Paneth cells play critical roles in host-microbial interactions and epithelial homeostasis. The ra...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Lueschow, Shiloh R., Stumphy, Jessica, Gong, Huiyu, Kern, Stacy L., Elgin, Timothy G., Underwood, Mark A., Kalanetra, Karen M., Mills, David A., Wong, Melissa H., Meyerholz, David K., Good, Misty, McElroy, Steven J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166990/
https://ncbi.nlm.nih.gov/pubmed/30273395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204967
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