Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes seen in neonatal necrotizing enterocolitis

Necrotizing enterocolitis (NEC) remains the leading cause of gastrointestinal morbidity and mortality in premature infants. Human and animal studies suggest a role for Paneth cells in NEC pathogenesis. Paneth cells play critical roles in host-microbial interactions and epithelial homeostasis. The ra...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Lueschow, Shiloh R., Stumphy, Jessica, Gong, Huiyu, Kern, Stacy L., Elgin, Timothy G., Underwood, Mark A., Kalanetra, Karen M., Mills, David A., Wong, Melissa H., Meyerholz, David K., Good, Misty, McElroy, Steven J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166990/
https://ncbi.nlm.nih.gov/pubmed/30273395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204967
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