Circulating HLA-DR(+)CD4(+) effector memory T cells resistant to CCR5 and PD-L1 mediated suppression compromise regulatory T cell function in tuberculosis

Chronic T cell activation is a hallmark of pulmonary tuberculosis (PTB). The mechanisms underpinning this important phenomenon are however, poorly elucidated, though known to rely on control of T effector cells (Teff) by regulatory T cells (Treg). Our studies show that circulating natural Treg cells...

Fuld beskrivelse

Na minha lista:

Bibliografiske detaljer
Udgivet i:	PLoS Pathog
Main Authors:	Ahmed, Asma, Adiga, Vasista, Nayak, Soumya, Uday Kumar, J. Anto Jesuraj, Dhar, Chirag, Sahoo, Pravat Nalini, Sundararaj, Bharath K., Souza, George D., Vyakarnam, Annapurna
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science 2018
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6166982/ https://ncbi.nlm.nih.gov/pubmed/30231065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007289
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!

Circulating HLA-DR(+)CD4(+) effector memory T cells resistant to CCR5 and PD-L1 mediated suppression compromise regulatory T cell function in tuberculosis

Lignende værker