Circulating Mycobacterium tuberculosis DosR latency antigen-specific, polyfunctional, regulatory IL10(+) Th17 CD4 T-cells differentiate latent from active tuberculosis

The functional heterogeneity of T cell responses to diverse antigens expressed at different stages of Mycobacterium tuberculosis (Mtb) infection, in particular early secreted versus dormancy related latency antigens expressed later, that distinguish subjects with latent (LTBI), pulmonary (PTB) or ex...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rakshit, Srabanti, Adiga, Vasista, Nayak, Soumya, Sahoo, Pravat Nalini, Sharma, Prabhat Kumar, van Meijgaarden, Krista E., UK J., Anto Jesuraj, Dhar, Chirag, Souza, George D., Finak, Greg, De Rosa, Stephen C., Ottenhoff, Tom H. M., Vyakarnam, Annapurna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607261/
https://ncbi.nlm.nih.gov/pubmed/28931830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10773-5
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