Mitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate release

Hsp72 is a member of the 70-kD heat shock family of molecular chaperones (Hsp70s) that comprise a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD) connected by a linker that couples the exchange of adenosine diphosphate (ADP) for adenosine triphosphate (ATP) with the release of t...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Mukherjee, Manjeet, Sabir, Sarah, O’Regan, Laura, Sampson, Josephina, Richards, Mark W., Huguenin-Dezot, Nicolas, Ault, James R., Chin, Jason W., Zhuravleva, Anastasia, Fry, Andrew M., Bayliss, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166782/
https://ncbi.nlm.nih.gov/pubmed/30108182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aao2464
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