A Novel Differential Ion Mobility Device Expands the Depth of Proteome Coverage and the Sensitivity of Multiplex Proteomic Measurements

The depth of proteomic analyses is often limited by the overwhelming proportion of confounding background ions that compromise the identification and quantification of low abundance peptides. To alleviate these limitations, we present a new high field asymmetric waveform ion mobility spectrometry (F...

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Bibliografiske detaljer
Udgivet i:Mol Cell Proteomics
Main Authors: Pfammatter, Sibylle, Bonneil, Eric, McManus, Francis P., Prasad, Satendra, Bailey, Derek J., Belford, Michael, Dunyach, Jean-Jacques, Thibault, Pierre
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2018
Fag:
Technological Innovation and Resources
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166672/
https://ncbi.nlm.nih.gov/pubmed/30007914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.TIR118.000862
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