[(18)F]AV-1451 binding in vivo mirrors the expected distribution of TDP-43 pathology in the semantic variant of primary progressive aphasia

INTRODUCTION: Semantic dementia, including the semantic variant of primary progressive aphasia (svPPA), is strongly associated with TAR-DNA binding protein 43 (TDP-43) type C pathology. It provides a useful model in which to test the specificity of in vivo binding of the putative tau ligand [(18)F]A...

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Detalles Bibliográficos
Publicado en:J Neurol Neurosurg Psychiatry
Main Authors: Bevan-Jones, W R, Cope, Thomas E, Jones, P Simon, Passamonti, Luca, Hong, Young T, Fryer, Tim D, Arnold, Robert, Allinson, Kieren S J, Coles, Jonathan P, Aigbirhio, Franklin I, Patterson, Karalyn, O’Brien, John T, Rowe, James B
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2018
Assuntos:
Neurodegeneration
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166613/
https://ncbi.nlm.nih.gov/pubmed/28912300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2017-316402
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