The influence of β-amyloid on [(18)F]AV-1451 in semantic variant of primary progressive aphasia

OBJECTIVE: To compare [(18)F]AV-1451 uptake in the semantic variant of primary progressive aphasia (svPPA) to Alzheimer dementia, and determine whether increased uptake in svPPA is associated with the presence of β-amyloid (Aβ). METHODS: Thirty-one participants with svPPA underwent MRI and Pittsburg...

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Udgivet i:Neurology
Main Authors: Whitwell, Jennifer L., Martin, Peter R., Duffy, Joseph R., Clark, Heather M., Machulda, Mary M., Schwarz, Christopher G., Weigand, Stephen D., Sintini, Irene, Senjem, Matthew L., Ertekin-Taner, Nilufer, Botha, Hugo, Utianski, Rene L., Graff-Radford, Jonathan, Jones, David T., Boeve, Bradley F., Knopman, David S., Petersen, Ronald C., Jack, Clifford R., Lowe, Val J., Josephs, Keith A.
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6382367/
https://ncbi.nlm.nih.gov/pubmed/30635491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000006913
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