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[(18)F]AV‐1451 binding is increased in frontotemporal dementia due to C9orf72 expansion

The PET ligand [(18)F]AV‐1451 was developed to bind tau pathology in Alzheimer's disease, but increased binding has been shown in both genetic tauopathies and in semantic dementia, a disease strongly associated with TDP‐43 pathology. Here we assessed [(18)F]AV‐1451 binding in behavioral variant...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Bevan‐Jones, Richard W., Cope, Thomas E., Jones, Simon P., Passamonti, Luca, Hong, Young T., Fryer, Tim, Arnold, Robert, Coles, Jonathan P., Aigbirhio, Franklin A., Patterson, Karalyn, O'Brien, John T., Rowe, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6186940/
https://ncbi.nlm.nih.gov/pubmed/30349864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.631
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