[(18)F]AV-1451 binding in vivo mirrors the expected distribution of TDP-43 pathology in the semantic variant of primary progressive aphasia

INTRODUCTION: Semantic dementia, including the semantic variant of primary progressive aphasia (svPPA), is strongly associated with TAR-DNA binding protein 43 (TDP-43) type C pathology. It provides a useful model in which to test the specificity of in vivo binding of the putative tau ligand [(18)F]A...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurol Neurosurg Psychiatry
Prif Awduron: Bevan-Jones, W R, Cope, Thomas E, Jones, P Simon, Passamonti, Luca, Hong, Young T, Fryer, Tim D, Arnold, Robert, Allinson, Kieren S J, Coles, Jonathan P, Aigbirhio, Franklin I, Patterson, Karalyn, O’Brien, John T, Rowe, James B
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMJ Publishing Group 2018
Pynciau:
Neurodegeneration
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166613/
https://ncbi.nlm.nih.gov/pubmed/28912300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2017-316402
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