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Comparative In Vitro and In Silico Analysis of the Selectivity of Indirubin as a Human Ah Receptor Agonist

The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that modulates gene expression following its binding and activation by structurally diverse chemicals. Species differences in AhR functionality have been observed, with the mouse AhR (mAhR) and human AhR (hAhR) exhibiting...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Faber, Samantha C., Soshilov, Anatoly A., Giani Tagliabue, Sara, Bonati, Laura, Denison, Michael S.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6165432/
https://ncbi.nlm.nih.gov/pubmed/30201897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19092692
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