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Deciphering Dimerization Modes of PAS Domains: Computational and Experimental Analyses of the AhR:ARNT Complex Reveal New Insights Into the Mechanisms of AhR Transformation

The Aryl hydrocarbon Receptor (AhR) is a transcription factor that mediates the biochemical response to xenobiotics and the toxic effects of a number of environmental contaminants, including dioxins. Recently, endogenous regulatory roles for the AhR in normal physiology and development have also bee...

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Библиографические подробности
Опубликовано в: :PLoS Comput Biol
Главные авторы: Corrada, Dario, Soshilov, Anatoly A., Denison, Michael S., Bonati, Laura
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905635/
https://ncbi.nlm.nih.gov/pubmed/27295348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004981
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