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Molecular modeling of the AhR structure and interactions can shed light on ligand-dependent activation and transformation mechanisms

Molecular modeling has given important contributions to elucidation of the main stages in the AhR signal transduction pathway. Despite the lack of experimentally determined structures of the AhR functional domains, information derived from homologous systems has been exploited for modeling their str...

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Detalles Bibliográficos
Publicado en:Curr Opin Toxicol
Main Authors: Bonati, Laura, Corrada, Dario, Tagliabue, Sara Giani, Motta, Stefano
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421400/
https://ncbi.nlm.nih.gov/pubmed/28497129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cotox.2017.01.011
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