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Pyridone luciferins and mutant luciferases for bioluminescence imaging
New applications of bioluminescence imaging require an expanded set of luciferase enzymes and luciferin substrates. Here we report two novel luciferins for use in vitro and in cells. These molecules comprise regioisomeric pyridone cores that can be accessed from a common synthetic route. The analogs...
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| Publicado en: | Chembiochem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6163054/ https://ncbi.nlm.nih.gov/pubmed/29384255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201700542 |
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