PDGFR and IGF-1R Inhibitors Induce a G2/M Arrest and Subsequent Cell Death in Human Glioblastoma Cell Lines

Glioblastomas are highly resistant to radiation and chemotherapy. Currently, there are no effective therapies for this type of tumor. Signaling mechanisms initiated by PDGFR and IGF-1R are important in glioblastoma, and inhibition of the signal transduction pathways initiated by these receptors coul...

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Publicado no:Cells
Main Authors: Carrasco-Garcia, Estefania, Martinez-Lacaci, Isabel, Mayor-López, Leticia, Tristante, Elena, Carballo-Santana, Mar, García-Morales, Pilar, Ventero Martin, Maria Paz, Fuentes-Baile, Maria, Rodriguez-Lescure, Álvaro, Saceda, Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162497/
https://ncbi.nlm.nih.gov/pubmed/30200644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7090131
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