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PDGFR and IGF-1R Inhibitors Induce a G2/M Arrest and Subsequent Cell Death in Human Glioblastoma Cell Lines

Glioblastomas are highly resistant to radiation and chemotherapy. Currently, there are no effective therapies for this type of tumor. Signaling mechanisms initiated by PDGFR and IGF-1R are important in glioblastoma, and inhibition of the signal transduction pathways initiated by these receptors coul...

詳細記述

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書誌詳細
出版年:Cells
主要な著者: Carrasco-Garcia, Estefania, Martinez-Lacaci, Isabel, Mayor-López, Leticia, Tristante, Elena, Carballo-Santana, Mar, García-Morales, Pilar, Ventero Martin, Maria Paz, Fuentes-Baile, Maria, Rodriguez-Lescure, Álvaro, Saceda, Miguel
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162497/
https://ncbi.nlm.nih.gov/pubmed/30200644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7090131
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