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PDGFR and IGF-1R Inhibitors Induce a G2/M Arrest and Subsequent Cell Death in Human Glioblastoma Cell Lines

Glioblastomas are highly resistant to radiation and chemotherapy. Currently, there are no effective therapies for this type of tumor. Signaling mechanisms initiated by PDGFR and IGF-1R are important in glioblastoma, and inhibition of the signal transduction pathways initiated by these receptors coul...

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Bibliografske podrobnosti
izdano v:Cells
Main Authors: Carrasco-Garcia, Estefania, Martinez-Lacaci, Isabel, Mayor-López, Leticia, Tristante, Elena, Carballo-Santana, Mar, García-Morales, Pilar, Ventero Martin, Maria Paz, Fuentes-Baile, Maria, Rodriguez-Lescure, Álvaro, Saceda, Miguel
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162497/
https://ncbi.nlm.nih.gov/pubmed/30200644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7090131
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