PDGFR and IGF-1R Inhibitors Induce a G2/M Arrest and Subsequent Cell Death in Human Glioblastoma Cell Lines

Glioblastomas are highly resistant to radiation and chemotherapy. Currently, there are no effective therapies for this type of tumor. Signaling mechanisms initiated by PDGFR and IGF-1R are important in glioblastoma, and inhibition of the signal transduction pathways initiated by these receptors coul...

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Pubblicato in:Cells
Autori principali: Carrasco-Garcia, Estefania, Martinez-Lacaci, Isabel, Mayor-López, Leticia, Tristante, Elena, Carballo-Santana, Mar, García-Morales, Pilar, Ventero Martin, Maria Paz, Fuentes-Baile, Maria, Rodriguez-Lescure, Álvaro, Saceda, Miguel
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162497/
https://ncbi.nlm.nih.gov/pubmed/30200644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7090131
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