Retinoids Issued from Hepatic Stellate Cell Lipid Droplet Loss as Potential Signaling Molecules Orchestrating a Multicellular Liver Injury Response

Hepatic stellate cells (HSCs) serve as the main body storage compartment for vitamin A through retinyl ester (RE)-filled lipid droplets (LDs). Upon liver injury, HSCs adopt a myofibroblastic phenotype characterized by an elevated expression of extracellular matrix proteins and a concomitant loss of...

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Vydáno v:Cells
Hlavní autoři: Bobowski-Gerard, Marie, Zummo, Francesco Paolo, Staels, Bart, Lefebvre, Philippe, Eeckhoute, Jérôme
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
Perspective
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162435/
https://ncbi.nlm.nih.gov/pubmed/30217095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7090137
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