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PIP5 Kinases Regulate Membrane Phosphoinositide and Actin Composition for Targeted Granule Secretion by Cytotoxic Lymphocytes

How cytotoxic T lymphocytes (CTLs) sense T cell receptor (TCR) signaling in order to specialize an area of plasma membrane for granule secretion is not understood. Here, we demonstrate that immune synapse formation led to rapid localized changes in the phosphoinositide composition of the plasma memb...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Immunity
Egile Nagusiak: Gawden-Bone, Christian M., Frazer, Gordon L., Richard, Arianne C., Ma, Claire Y., Strege, Katharina, Griffiths, Gillian M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cell Press 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162341/
https://ncbi.nlm.nih.gov/pubmed/30217409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.08.017
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