mTORC1 plays an important role in osteoblastic regulation of B-lymphopoiesis

Skeletal osteoblasts are important regulators of B-lymphopoiesis, serving as a rich source of factors such as CXCL12 and IL-7 which are crucial for B-cell development. Recent studies from our laboratory and others have shown that deletion of Rptor, a unique component of the mTORC1 nutrient-sensing c...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Martin, Sally K., Fitter, Stephen, El Khawanky, Nadia, Grose, Randall H., Walkley, Carl R., Purton, Louise E., Ruegg, Markus A., Hall, Michael N., Gronthos, Stan, Zannettino, Andrew C. W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162303/
https://ncbi.nlm.nih.gov/pubmed/30266921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32858-5
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